Improved diagnosis of pleural tuberculosis using the microscopic- observation drug-susceptibility technique.

نویسندگان

  • Marco Tovar
  • Mark J Siedner
  • Robert H Gilman
  • Carlos Santillan
  • Luz Caviedes
  • Teresa Valencia
  • Oswaldo Jave
  • A Rod Escombe
  • David A J Moore
  • Carlton A Evans
چکیده

Tests for pleural tuberculosis are insensitive and expensive. We compared nonproprietary microscopic-observation drug-susceptibility (MODS) culture with Löwenstein-Jensen culture for evaluation of pleural specimens. MODS culture was associated with greatly increased diagnostic sensitivity and shorter time to diagnosis, compared with Löwenstein-Jensen culture (sensitivity of culture of biopsy specimens, 81% vs.51%; time to diagnosis, 11 days vs. 24 days; P < .001). The MODS technique is inexpensive, allows drug-susceptibility testing, and is a considerably improved diagnostic method for pleural tuberculosis.

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عنوان ژورنال:
  • Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

دوره 46 6  شماره 

صفحات  -

تاریخ انتشار 2008